476Heterogeneous Vancomycin-Intermediate Coagulase-Negative Staphylococci in Neonates: Does treatment with Linezolid improve outcomes?
نویسندگان
چکیده
Staphylococci in Neonates: Does treatment with Linezolid improve outcomes? Ana Chelène Blanchard, MDCM; Céline Laferrière, MD; Isabelle Goyer, Pharm ; Philippe Ovetchkine, MD; Ahmed Moussa, MD; Beatrice Da Silva; Jasmine Swet Yee Chong, BSc Microbiology; Caroline Quach, MDMSc; Department of Pediatrics; Pediatrics, University of Montreal / CHU Sainte Justine, Montreal, QC, Canada; Microbiology, CHU Sainte-Justine, Montréal, QC, Canada; Pharmacy, CHU Sainte Justine / University of Montreal, Montreal, QC, Canada; Pediatric Infectious Diseases, CHU Sainte Justine / University of Montreal, Montreal, QC, Canada; Neonatology, CHU Sainte Justine / University of Montreal, Montreal, QC, Canada; Pediatrics, CHU Sainte Justine / University of Montreal, Montreal, QC, Canada; Epidemiology, McGill University, Montreal, QC, Canada; Division of Infectious Diseases; The Montreal Children’s Hospital, Montreal, QC, Canada
منابع مشابه
Comparative in vitro activities and postantibiotic effects of the oxazolidinone compounds eperezolid (PNU-100592) and linezolid (PNU-100766) versus vancomycin against Staphylococcus aureus, coagulase-negative staphylococci, Enterococcus faecalis, and Enterococcus faecium.
The activities of the oxazolidinone antibacterial agents eperezolid (PNU-100592) and linezolid (PNU-100766) were compared with that of vancomycin against clinical isolates of methicillin-susceptible and -resistant Staphylococcus aureus (n = 200), coagulase-negative staphylococci (n = 100), and vancomycin-susceptible and -resistant Enterococcus faecalis and Enterococcus faecium (n = 50). Eperezo...
متن کاملEfficacy of vancomycin versus linezolid against coagulase-negative staphylococci in various clinical specimens.
BACKGROUND Worldwide increase in antibiotic resistance has become one of the major problems. Optimal and rationale use of antibiotic is important to prevent resistance against most of the bacteria including Coagulase-negative Staphylococci (CoNS), which has now been recognized as an important pathogen for nosocomial infections. This study was carried out to determine efficacy of vancomycin and ...
متن کاملIn vitro susceptibility to methicillin, vancomycin and linezolid of staphylococci isolated from bloodstream infections in eastern Turkey
Staphylococcus species are one of the major causes of bacterial bloodstream infections. Multi-resistant staphylococci infections are major therapeutic problems. This study was aimed to detect methicillin, linezolid and vancomycin susceptibilities of Staphylococcus isolates. A total of 870 Staphylococcus strains isolated from blood cultures of hospitalized patients with BSI. Antimicrobial suscep...
متن کاملAntimicrobial Activity of Ceftaroline Tested against Staphylococci with Reduced Susceptibility
Vancomycin, linezolid, and daptomycin are very active against staphylococci, but isolates with decreased susceptibility to these antimicrobial agents are isolated sporadically. A total of 19,350 Staphylococcus aureus isolates (51% methicillin resistant [MRSA]) and 3,270 coagulase-negative staphylococci (CoNS) were collected consecutively from 82 U.S. medical centers from January 2008 to Decembe...
متن کاملClinically significant Coagulase Negative Staphylococci and their antibiotic resistance pattern in a tertiary care hospital.
OBJECTIVES To identify various species of coagulase negative staphylococci involved in neonatal septicaemia and determine their antimicrobial resistance pattern. METHODS The prospective descriptive study was carried out from January 2012 to October 2013, at Umm Al-Qura University, Makkah, Saudi Arabia, and comprised clinical isolates of coagulase negative staphylococci recovered from the bloo...
متن کامل